Table 1 Characteristics of lung cancer cases and controls
Characteristic | Cases (n = 626) n (%) | Controls (n = 626) n (%) | P a |
|---|---|---|---|
Sex | |||
Male | 541 (86.4) | 541 (86.4) | |
Female | 85 (13.6) | 85 (13.6) | 1.000 |
Age (yrs), mean (SD) | 64.48 (10.96) | 63.61 (11.21) | 0.161 |
median (IQR) | 65.00 (17.00) | 64.00 (18.00) | 0.172 |
Hospital areab | |||
Gijon (Cabueñes Hospital) | 355 (56.7) | 355 (56.7) | |
Aviles (San Agustin Hospital) | 176 (28.1) | 176 (28.1) | |
Oviedo (General Hospital) | 58 (9.3) | 58 (9.3) | |
Mieres (Alvarez-Buylla Hospital) | 37 (5.9) | 37 (5.9) | 1.000 |
Smoking Status | |||
Never | 47 (7.5) | 182 (29.1) | |
Ever | 579 (92.5) | 444 (70.9) | <0.001 |
Former | 181 (31.3) | 227 (51.1) | |
Current | 398 (68.7) | 217 (48.9) | <0.001 |
PYc, mean (SD) | 62.01 (35.34) | 38.27 (31.96) | <0.001 |
median (IQR) | 55.00 (40.75) | 32.00 (35.86) | <0.001 |
Smoking | |||
Never | 47 (7.6) | 182 (29.6) | |
Former < 38 PY | 62 (10.0) | 151 (24.6) | |
Current < 38 PY | 72 (11.7) | 102 (16.6) | |
Former ≥ 38 PY | 117 (18.9) | 70 (11.4) | |
Current ≥ 38 PY | 320 (51.8) | 109 (17.8) | <0.001 |
Family history of cancer | |||
None | 338 (56.2) | 371 (59.8) | |
Other cancers | 190 (31.6) | 204 (32.9) | |
Lung cancer | 73 (12.2) | 45 (7.3) | 0.015 |
Histologic type | |||
Squamous cell carcinoma | 242 (39.4) | ||
Adenocarcinoma | 182 (29.6) | ||
Small cell carcinoma | 109 (17.7) | ||
Large cell carcinoma | 18 (2.9) | ||
Non-differentiated | 42 (6.8) | ||
Others | 14 (2.3) | ||
Clinical diagnosis | 8 (1.3) | ||
Missing | 11 | ||
Worker in high-risk occupation | |||
Never | 220 (35.4) | 245 (39.3) | |
Ever | 401 (64.6) | 379 (60.7) | 0.162 |
Time in high-risk occupationd, mean (SD) | 26.31 (14.59) | 24.24 (13.95) | 0.045 |
Median (IQR) | 29.00 (25.00) | 26.00 (23.00) | 0.036 |
Population living in their last-residence | |||
for more than 5 years | 547 (88.90) | 552 (89.30) | 0.903 |
for more than 10 years | 492 (80.00) | 495 (80.10) | 0.977 |