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Table 2 Odds ratios of lung cancer by histologic type and distribution of potential confounding variables

From: Lung cancer risk and pollution in an industrial region of Northern Spain: a hospital-based case-control study

  Total Squamous cell carcinoma Adenocarcinoma Small cell carcinoma
  Controls Cases OR (95%CI)a P-value Cases OR (95%CI)a P-value Cases OR (95%CI)a P-value Cases OR (95%CI)a P-value
  N N    N    N    N   
Smoking            
   Never 182 47 Reference   7 Reference   21 Reference   6 Reference  
   Former < 38 PY 151 62 2.84 (1.71-4.74)   22 7.63 (2.75-21.16)   14 1.63 (0.78-3.40)   6 2.34 (0.77-7.09)  
   Current < 38 PY 70 72 5.29 (3.14-8.91)   23 11.65 (4.10-33.06)   24 3.71 (1.85-7.44)   7 5.46 (1.91-15.57)  
   Former38 PY 102 117 13.00 (7.63-22.15)   53 36.63 (13.14-102.13)   28 7.64 (3.65-16.03)   16 12.88 (4.38-37.87)  
   Current38 PY 109 320 23.74 (14.48-38.94) <0.001b 111 57.78 (21.46-155.58) <0.001b 69 12.12 (6.25-23.52) <0.001b 54 28.15 (10.65-74.39) <0.001b
Family history of cancer           
   None 371 338 Reference   108 Reference   90 Reference   57 Reference  
   Other cancers 204 190 1.02 (0.77-1.36) 0.607 77 1.46 (0.99-2.15) 0.161 48 0.86 (0.57-1.30) 0.885 21 0.67 (0.39-1.16) 0.319
   Lung cancer 45 73 1.59 (1.00-2.51) 0.083 25 2.52 (1.38-4.61) 0.035 16 1.38 (0.72-2.66) 0.080 9 1.33 (0.59-3.01) 0.430
Occupation              
   Never 245 220 Reference   68 Reference   76 Reference   47 Reference  
   < 35 years 274 257 1.09 (0.79-1.49)   112 1.36 (0.88-2.10)   61 0.97 (0.61-1.54)   42 0.76 (0.44-1.31)  
   ≥ 35 years 102 140 1.42 (0.96-2.10) 0.082b 60 1.74 (1.04-2.92) 0.048b 43 1.63 (0.94-2.82) 0.089b 17 0.75 (0.37-1.53) 0.384b
  1. aORs were estimated from a multiple logistic regression model that included age, sex, hospital area, tobacco consumption, family history of cancer, occupation, and exposure area
  2. bTest for trend