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Table 4 Usual power of the cluster detection methods

From: Detection of clusters of a rare disease over a large territory: performance of cluster detection methods

  

"Small Clusters"1

"Moderate Clusters"1

"Large Clusters"1

  

#1

#2

#3

#4

#5

#6

#7

#8

#9

  

Linear

U-Shaped

Compact

Linear

U-Shaped

Compact

Linear

U-Shaped

Compact

  

No LZ = 6

No. LZ = 10

No. LZ = 8

No. LZ = 7

No. LZ = 7

No. LZ = 11

No. LZ = 12

No. LZ = 16

No. LZ = 13

RR = 1.5

Scan-c

0.18

0.16

0.14

0.30

0.32

0.40

0.84

0.85

0.83

 

Scan-e0

0.11

0.11

0.11

0.26

0.26

0.36

0.83

0.83

0.79

 

FleX

0.12

0.15

0.16

0.25

0.29

0.36

0.78

0.74

0.76

 

GA-1

0.14

0.11

0.10

0.33

0.30

0.44

0.87

0.87

0.83

 

Double

0.14

0.13

0.13

0.26

0.25

0.39

0.82

0.79

0.78

 

Mlink

0.65

0.60

0.60

0.71

0.73

0.79

0.95

0.96

0.96

RR = 2.0

Scan-c

0.46

0.49

0.52

0.94

0.96

1.00

1.00

1.00

1.00

 

Scan-e0

0.51

0.51

0.50

0.95

0.95

0.98

1.00

1.00

1.00

 

FleX

0.52

0.57

0.52

0.93

0.92

0.97

1.00

1.00

1.00

 

GA-1

0.32

0.41

0.43

0.95

0.95

1.00

1.00

1.00

1.00

 

Double

0.44

0.42

0.48

0.92

0.90

0.98

1.00

1.00

1.00

 

Mlink

0.83

0.82

0.85

1.00

1.00

1.00

1.00

1.00

1.00

RR = 3.0

Scan-c

0.97

0.99

0.99

1.00

1.00

1.00

1.00

1.00

1.00

 

Scan-e0

0.99

0.99

0.99

1.00

1.00

1.00

1.00

1.00

1.00

 

FleX

0.98

1.00

0.99

1.00

1.00

1.00

1.00

1.00

1.00

 

GA-1

0.92

0.98

0.98

1.00

1.00

1.00

1.00

1.00

1.00

 

Double

0.98

0.97

0.99

1.00

1.00

1.00

1.00

1.00

1.00

 

Mlink

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

  1. Scan-c: circular scan method, Scan-e 0: standard elliptic scan method, FleX: unrestricted flexible scan method, GA-1: strongly penalized genetic algorithm, Double and Mlink: dynamic minimum spanning tree method with double and maximum link connections, respectively. No. LZ: size of living zones in the cluster (number of living zones); RR: relative risk in the true cluster. Results based on 250 Monte Carlo replications.
  2. 1 "small", "moderate" and "large" clusters are clusters with about 20, 45 and 115 cases of childhood acute leukemia over the period 1990-2006, respectively.