Skip to main content

Table 4 Usual power of the cluster detection methods

From: Detection of clusters of a rare disease over a large territory: performance of cluster detection methods

   "Small Clusters"1 "Moderate Clusters"1 "Large Clusters"1
   #1 #2 #3 #4 #5 #6 #7 #8 #9
   Linear U-Shaped Compact Linear U-Shaped Compact Linear U-Shaped Compact
   No LZ = 6 No. LZ = 10 No. LZ = 8 No. LZ = 7 No. LZ = 7 No. LZ = 11 No. LZ = 12 No. LZ = 16 No. LZ = 13
RR = 1.5 Scan-c 0.18 0.16 0.14 0.30 0.32 0.40 0.84 0.85 0.83
  Scan-e0 0.11 0.11 0.11 0.26 0.26 0.36 0.83 0.83 0.79
  FleX 0.12 0.15 0.16 0.25 0.29 0.36 0.78 0.74 0.76
  GA-1 0.14 0.11 0.10 0.33 0.30 0.44 0.87 0.87 0.83
  Double 0.14 0.13 0.13 0.26 0.25 0.39 0.82 0.79 0.78
  Mlink 0.65 0.60 0.60 0.71 0.73 0.79 0.95 0.96 0.96
RR = 2.0 Scan-c 0.46 0.49 0.52 0.94 0.96 1.00 1.00 1.00 1.00
  Scan-e0 0.51 0.51 0.50 0.95 0.95 0.98 1.00 1.00 1.00
  FleX 0.52 0.57 0.52 0.93 0.92 0.97 1.00 1.00 1.00
  GA-1 0.32 0.41 0.43 0.95 0.95 1.00 1.00 1.00 1.00
  Double 0.44 0.42 0.48 0.92 0.90 0.98 1.00 1.00 1.00
  Mlink 0.83 0.82 0.85 1.00 1.00 1.00 1.00 1.00 1.00
RR = 3.0 Scan-c 0.97 0.99 0.99 1.00 1.00 1.00 1.00 1.00 1.00
  Scan-e0 0.99 0.99 0.99 1.00 1.00 1.00 1.00 1.00 1.00
  FleX 0.98 1.00 0.99 1.00 1.00 1.00 1.00 1.00 1.00
  GA-1 0.92 0.98 0.98 1.00 1.00 1.00 1.00 1.00 1.00
  Double 0.98 0.97 0.99 1.00 1.00 1.00 1.00 1.00 1.00
  Mlink 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00
  1. Scan-c: circular scan method, Scan-e 0: standard elliptic scan method, FleX: unrestricted flexible scan method, GA-1: strongly penalized genetic algorithm, Double and Mlink: dynamic minimum spanning tree method with double and maximum link connections, respectively. No. LZ: size of living zones in the cluster (number of living zones); RR: relative risk in the true cluster. Results based on 250 Monte Carlo replications.
  2. 1 "small", "moderate" and "large" clusters are clusters with about 20, 45 and 115 cases of childhood acute leukemia over the period 1990-2006, respectively.