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Table 5 Power to detect at least one LZ in the true cluster.

From: Detection of clusters of a rare disease over a large territory: performance of cluster detection methods

  

"Small Clusters"1

"Moderate Clusters"1

"Large Clusters"1

  

#1

#2

#3

#4

#5

#6

#7

#8

#9

  

Linear

U-Shaped

Compact

Linear

U-Shaped

Compact

Linear

U-Shaped

Compact

  

No. LZ = 6

No. LZ = 10

No. LZ = 8

No. LZ = 7

No. LZ = 7

No. LZ = 11

No. LZ = 12

No. LZ = 16

No. LZ = 13

RR = 1.5

Scan-c

0.04

0.07

0.05

0.22

0.21

0.34

0.83

0.82

0.80

 

Scan-e0

0.03

0.02

0.05

0.19

0.19

0.31

0.81

0.81

0.76

 

FleX

0.04

0.07

0.07

0.17

0.19

0.28

0.76

0.72

0.72

 

GA-1

0.02

0.05

0.02

0.24

0.23

0.36

0.85

0.86

0.80

 

Double

0.03

0.06

0.05

0.17

0.16

0.32

0.80

0.76

0.74

 

Mlink

0.11

0.13

0.11

0.34

0.34

0.50

0.90

0.91

0.88

RR = 2.0

Scan-c

0.38

0.41

0.44

0.94

0.92

1.00

1.00

1.00

1.00

 

Scan-e0

0.43

0.39

0.46

0.94

0.94

0.98

1.00

1.00

1.00

 

FleX

0.44

0.54

0.47

0.92

0.91

0.97

1.00

1.00

1.00

 

GA-1

0.25

0.37

0.34

0.94

0.92

0.99

1.00

1.00

1.00

 

Double

0.38

0.36

0.42

0.91

0.88

0.98

1.00

1.00

1.00

 

Mlink

0.59

0.57

0.58

0.96

0.96

0.99

1.00

1.00

1.00

RR = 3.0

Scan-c

0.97

0.99

0.99

1.00

1.00

1.00

1.00

1.00

1.00

 

Scan-e0

0.99

0.95

0.99

1.00

1.00

1.00

1.00

1.00

1.00

 

FleX

0.98

0.99

0.99

1.00

1.00

1.00

1.00

1.00

1.00

 

GA-1

0.92

0.98

0.98

1.00

1.00

1.00

1.00

1.00

1.00

 

Double

0.98

0.96

0.98

1.00

1.00

1.00

1.00

1.00

1.00

 

Mlink

0.99

0.99

1.00

1.00

1.00

1.00

1.00

1.00

1.00

  1. Scan-c: circular scan method, Scan-e 0: standard elliptic scan method, FleX: unrestricted flexible scan method, GA-1: strongly penalized genetic algorithm, Double and Mlink: dynamic minimum spanning tree method with double and maximum link connections, respectively. No. LZ: size of the cluster (number of living zones); RR: relative risk in the true cluster. Results based on 250 Monte Carlo replications.
  2. 1 "small", "moderate" and "large" clusters are clusters with about 20, 45 and 115 cases of childhood acute leukemia over the period 1990-2006, respectively.