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Table 1 Candidate clusters of T1D cases discovered by the FGBASE using cases from the Isis-Diab cohort

From: An open source software for fast grid-based data-mining in spatial epidemiology (FGBASE)

Cluster candidate Cluster candidate 1 Cluster candidate 2 Cluster candidate 3 Cluster candidate 4
Location Next to Le Havre Next to Dunkerque Next to Toulouse Next to Nantes
LAEA -ETRS89 grid coordinates of the rectangular zone: [(3610,2979), (3610,2981), (3608,2981), (3608,2979)] [(3774,3126), (3774,3130), (3783,3130), (3783,3126)] [(3627,2313), (3627,2315), (3631,2315), (3631,2313)] [(3446,2746), (3446,2750), (3453,2750), (3453,2746)]
WGS84 coordinates of rectangular zone: [(0.15368,49.4943), (0.150047,49.5121), (0.122639,49.5097), (0.126282,49.4919)] [(2.19376,50.9823), (2.18771,51.018), (2.31538,51.0265), (2.32132,50.9908)] [(1.40999,43.5677), (1.40733,43.5856), (1.45649,43.5897), (1.45914,43.5718)] [(1.59501,47.2094), (-1.60299,47.2449), (-1.51148,47.2548), (-1.5035,47.2192)]
Number of cases 8 cases 13 cases 13 cases 41 cases
Number of controls 3 controls 0 controls 4 controls 16 controls
log of the numerator of Kulldorff’s likelihood ratio: -6240.36 -6235.35 -6238.47 -6235.09
  1. Using the data-driven option of the FGBASE software, zones most likely to be clusters of T1D cases where discovered in the vicinity of the cities of Le Havre, Dunkerque, Toulouse and Nantes.