The geographic distribution of melanoma incidence in Massachusetts, adjusted for covariates

Table 2 Age-adjusted male invasive melanoma statistics for space-time analyses of Massachusetts, 1990–1999.

Highs	1	2	3	4	5	8	9
Time frame	95–99	95–99	95–99	97–99	98–99	96–99	98–99
No Covariate adjustment
Obs¹	360	474	469	54	44	*	*
RR²	2.28	1.88	1.65	2.71	3.15	*	*
p-value	<0.0001	<0.0001	<0.0001	0.0003	0.0002	*	*
Percent Urban adjustment
Obs¹	378	474	452	54	185³	*	*
RR²	1.99	1.86	1.63	2.80	1.61	*	*
p-value	<0.0001	<0.0001	<0.0001	0.0004	0.001	*	*
SES adjustment
Obs¹	369	403⁶	*	64	*	318	186
RR²	2.22	1.78	*	2.36	*	1.44	1.78
p-value	<0.0001	<0.0001	*	0.002	*	0.0003	<0.0001
SES & Percent Urban adjustment
Obs¹	354⁹	356²	*	64	*	318	188
RR²	1.85	1.71	*	2.42	*	1.48	1.80
P-value	<0.0001	<0.0001	*	0.0004	*	<0.0001	<0.0001
Lows	A	B	C	D	E	F	H	J	K	L
Time frame	90–99	90–98	90–97	90–95	90–96	91–99	91–92	90–91	90–91	90–96
No Covariates adjustment
Obs¹	157	47	60	64	154	26	79	*	*	*
RR²	0.49	0.36	0.43	0.44	0.52	0.37	0.56	*	*	*
p-value	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	0.002	0.010	*	*	*
Percent Urban adjustment
Obs¹	142⁴	47	60	164⁵	229	*	*	48	*	*
RR²	0.49	0.35	0.44	0.61	0.58	*	*	0.51	*	*
p-value	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	*	*	0.0497	*	*
SES adjustment
Obs¹	177⁷	*	12	254⁵	*	*	79⁸	46	42	203
RR²	0.64	*	0.29	0.64	*	*	0.47	0.41	0.43	0.70
p-value	0.0002	*	0.044	<0.0001	*	*	<0.0001	<0.0001	0.0002	0.029
SES & Percent Urban adjustment
Obs¹	176⁷	*	*	201	*	*	79⁸	37	41	*
RR²	0.64	*	*	0.68	*	*	0.48	0.35	0.43	*
P-value	<0.0001	*	*	0.001	*	*	<0.0001	<0.0001	<0.0001	*

¹Obs = observed cases. ²RR = relative risk. ³The time frame for High 5 when adjusting for percent urban is 97–99. ⁴The time frame from Low A when adjusting for percent urban is 90–95. ⁵The time frame for Low D when adjusting for percent urban and SES separately is 90–96. ⁶The time frame for High 2 when adjusting for SES and SES with percent urban is 96–99. ⁷The time frame for Low A when adjusting for SES and SES with percent urban is 90–94. ⁸The time frame for Low H when adjusting for SES and SES with percent urban is 90–92. ⁹The time frame for High 1 when adjusting for SES and percent urban is 96–99. *Cluster not significant for this analysis.

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