Table 1 Prevalence odds ratio for congenital anomalies associated with maternal exposure to the emissions of the incinerator plant of Reggio Emilia, northern Italy, 1998–2006
Area | Cases % (n) | Controls % (n) | Odds ratio1 |
|---|---|---|---|
All anomalies | |||
A (low exposure) | 89.0 (203) | 90.4 (206) | 1.00 (referent) |
B (medium exposure) | 7.9 (18) | 5.3 (12) | 1.49 (0.70–3.19) |
C (high exposure) | 3.1 (7) | 4.3 (10) | 0.66 (0.25–1.79) |
P trend 0.881 | |||
Overall exposed area (B+C) | 11.0 (25) | 9.6 (22) | 1.11 (0.60–2,04) |
Cardiovascular system | |||
A (low exposure) | 9.6 (87) | 90.4 (206) | 1.00 (referent) |
B (medium exposure) | 6.3 (6) | 5.3 (12) | 0.91 (0.36–2.31) |
C (high exposure) | 3.1 (3) | 4.3 (10) | 0.77 (0.22–2.77) |
P trend 0.666 | |||
Overall exposed area (B+C) | 9.4 (9) | 9.6 (22) | 0.86 (0.40–1.86) |
Nervous system | |||
A (low exposure) | 95.7 (22) | 90.4 (206) | 1.00 (referent) |
B (medium exposure) | 4.3 (1) | 5.3 (12) | 0.64 (0.83–4.93) |
C (high exposure) | 0.0 (0) | 4.3 (10) | -2 |
P trend 0.344 | |||
Overall exposed area (B+C) | 4.3 (1) | 9.6 (22) | 0.41 (0.05–3.17) |
Chromosomal | |||
A (low exposure) | 85.4 (35) | 90.4 (206) | 1.00 (referent) |
B (medium exposure) | 12.2 (5) | 5.3 (12) | 2.53 (0.88–7.24) |
C (high exposure) | 2.4 (1) | 4.3 (10) | 0.77 (0.10–6.14) |
P trend 0.486 | |||
Overall exposed area (B+C) | 14.6 (6) | 9.6 (22) | 1.82 (0.70–4.72) |
Genito-urinary | |||
A (low exposure) | 90.4 (19) | 90.4 (206) | 1.00 (referent) |
B (medium exposure) | 4.8 (1) | 5.3 (12) | 0.65 (0.08–5.05) |
C (high exposure) | 4.8 (1) | 4.3 (10) | 1.08 (0.14–8.68) |
P trend 0.904 | |||
Overall exposed area (B+C) | 9.6 (2) | 9.6 (22) | 0.82 (0.18–3.67) |
Musculoskeletal | |||
A (low exposure) | 87.2 (34) | 90.4 (206) | 1.00 (referent) |
B (medium exposure) | 10.3 (4) | 5.3 (12) | 1.52 (0.49–4.67) |
C (high exposure) | 2.5 (1) | 4.3 (10) | 0.56 (0.07–4.47) |
P trend 0.928 | |||
Overall exposed area (B+C) | 12.8 (5) | 9.6 (22) | 1.13 (0.41–3.10) |
Clefts2,3 | |||
A (low exposure) | 100.0 (4) | 90.4 (206) | 1.00 (referent) |
Overall exposed area (B+C) | 0.0 (0) | 9.6 (22) | - |
Eye2 | |||
A (low exposure) | 85.7 (6) | 90.4 (206) | 1.00 (referent) |
Overall exposed area (B+C) | 14.3 (1) | 9.6 (22) | 1.78 (0.20–5.65) |
Other and unspecified congenital anomalies2 | |||
A (low exposure) | 87.5 (14) | 90.4 (206) | 1.00 (referent) |
Overall exposed area (B+C) | 12.5 (2) | 9.6 (22) | 1.11 (0.24–5.10) |