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Table 1 Simulation results for cluster model A (one circular cluster, 10% of total area) with a mean survival time of 5

From: Optimizing the maximum reported cluster size in the spatial scan statistic for survival data

 

% of cens

 

Maximum reported cluster size (MRCS)

Default Setting

3%

4%

5%

6%

8%

10%

12%

15%

20%

25%

30%

35%

40%

45%

50%

Overall

Circular window

10%

Frequency

2

5

15

22

48

657

110

76

23

15

8

4

2

1

1

 

989

Sensitivity

0.013

0.333

0.600

0.576

0.635

0.972

0.944

0.983

0.978

0.978

0.979

1.000

1.000

1.000

1.000

0.934

0.928

PPV

0.500

1.000

0.931

0.957

0.885

0.989

0.814

0.670

0.503

0.428

0.322

0.286

0.235

0.222

0.188

0.909

0.903

30%

Frequency

0

5

6

32

27

540

162

75

77

34

6

3

3

1

1

 

972

Sensitivity

–

0.367

0.389

0.563

0.599

0.957

0.937

0.960

0.961

0.995

1.000

1.000

1.000

1.000

1

0.923

0.906

PPV

–

0.950

0.911

0.974

0.783

0.968

0.812

0.700

0.524

0.430

0.339

0.271

0.234

0.214

0.188

0.852

0.845

50%

Frequency

0

9

0

120

16

367

209

159

56

32

8

7

1

2

0

 

986

Sensitivity

–

0.333

-

0.504

0.490

0.972

0.896

0.984

0.946

0.969

1.000

1.000

1.000

0.917

-

0.886

0.875

PPV

–

1.000

-

0.991

0.716

0.977

0.774

0.711

0.479

0.419

0.327

0.301

0.231

0.165

-

0.830

0.824

70%

Frequency

0

20

5

18

0

531

234

5

8

31

29

6

3

16

12

 

918

Sensitivity

–

0.333

0.333

0.500

-

0.970

0.828

0.667

0.979

0.844

0.994

1.000

0.889

0.969

0.986

0.902

0.831

PPV

–

1.000

1

0.986

-

0.997

0.708

0.500

0.522

0.349

0.319

0.269

0.219

0.208

0.191

0.841

0.837

Elliptical window

10%

Frequency

1

4

9

17

74

430

241

124

46

22

5

5

4

1

2

 

985

Sensitivity

0.010

0.417

0.482

0.510

0.701

0.957

0.974

0.989

0.989

1.000

1.000

0.967

1.000

1.000

1.000

0.934

0.920

PPV

1.000

1

0.963

1.000

0.962

0.969

0.823

0.689

0.522

0.399

0.326

0.279

0.238

0.207

0.185

0.853

0.847

30%

Frequency

0

3

1

28

118

248

247

179

85

43

12

3

2

0

2

 

971

Sensitivity

–

0.333

0.333

0.500

0.675

0.940

0.942

0.990

0.973

0.996

0.986

1.000

0.917

-

1.000

0.908

0.886

PPV

–

1

1.000

0.988

0.968

0.949

0.799

0.690

0.538

0.411

0.331

0.287

0.220

-

0.164

0.794

0.788

50%

Frequency

2

6

3

60

122

159

258

211

77

54

18

3

0

2

2

 

977

Sensitivity

0.027

0.389

0.556

0.500

0.669

0.957

0.913

0.982

0.957

0.988

0.982

1.000

-

1.000

1.000

0.883

0.865

PPV

1.000

1.000

0.933

0.992

0.986

0.955

0.791

0.696

0.522

0.411

0.321

0.288

-

0.182

0.185

0.781

0.779

70%

Frequency

0

4

0

53

184

212

169

85

91

30

25

20

20

7

13

 

913

Sensitivity

–

0.333

-

0.500

0.688

0.970

0.871

0.794

0.839

0.861

0.853

1.000

0.942

0.976

0.987

0.829

0.758

PPV

–

1.000

-

1.000

0.987

0.986

0.770

0.535

0.460

0.340

0.275

0.280

0.227

0.207

0.182

0.762

0.761

  1. % of cens, percentage of censoring; PPV, positive predictive value
  2. Cells most often selected as the optimal MRCS are shown in italics