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Table 2 Simulation results for cluster model B (one circular cluster, 30% of total area) with a mean survival time of 5

From: Optimizing the maximum reported cluster size in the spatial scan statistic for survival data

 

% of cens

 

Maximum reported cluster size (MRCS)

Default Setting

3%

4%

5%

6%

8%

10%

12%

15%

20%

25%

30%

35%

40%

45%

50%

Overall

Circular window

10%

Frequency

0

0

0

0

0

1

1

1

1

22

792

166

16

0

0

 

1000

Sensitivity

–

–

–

–

–

0.850

0.900

0.800

0.700

0.793

0.985

0.996

0.994

–

–

0.982

0.982

PPV

–

–

–

–

–

0.895

0.783

1.000

0.667

1.000

1.000

0.928

0.820

–

–

0.984

0.985

30%

Frequency

0

0

0

0

0

0

2

1

4

61

678

252

2

0

0

 

1000

Sensitivity

–

–

–

–

–

–

0.725

0.700

0.513

0.76

0.975

0.999

0.925

–

–

0.966

0.966

PPV

–

–

–

–

–

–

1.000

0.778

1.000

0.986

0.999

0.935

0.771

–

–

0.981

0.982

50%

Frequency

0

0

0

0

0

0

3

0

4

42

800

149

2

0

0

 

1000

Sensitivity

–

–

–

–

–

–

0.733

-

0.563

0.810

0.976

1.000

0.875

–

–

0.970

0.970

PPV

–

–

–

–

–

–

1.000

-

1.000

0.998

0.999

0.924

0.716

–

–

0.987

0.987

70%

Frequency

0

0

0

0

0

0

0

0

1

8

851

113

9

18

0

 

1000

Sensitivity

–

–

–

–

–

–

–

–

0.450

0.744

0.909

0.989

0.978

0.989

–

0.918

0.918

PPV

–

–

–

–

–

–

–

–

1.000

1.000

0.997

0.912

0.778

0.699

–

0.980

0.980

Elliptical window

10%

Frequency

0

0

0

0

0

0

1

4

3

24

757

176

31

3

1

 

1000

Sensitivity

–

–

–

–

–

–

0.700

0.875

0.717

0.796

0.981

0.988

0.987

1.000

1.000

0.977

0.977

PPV

–

–

–

–

–

–

0.875

0.825

0.955

0.995

0.997

0.921

0.796

0.732

0.606

0.975

0.976

30%

Frequency

0

0

0

0

0

0

2

0

13

90

619

262

12

1

1

 

1000

Sensitivity

–

–

–

–

–

–

0.750

-

0.627

0.761

0.970

0.992

0.983

1.000

1.000

0.952

0.953

PPV

–

–

–

–

–

–

0.917

-

1.000

0.991

0.997

0.926

0.766

0.741

0.606

0.974

0.973

50%

Frequency

0

0

0

0

0

0

1

0

6

74

750

156

10

2

1

 

1000

Sensitivity

–

–

–

–

–

–

0.750

-

0.633

0.764

0.967

0.990

0.970

1.000

1.000

0.954

0.953

PPV

–

–

–

–

–

–

1.000

-

1.000

0.995

0.995

0.916

0.765

0.742

0.625

0.980

0.979

70%

Frequency

0

0

0

0

0

0

0

1

3

15

666

156

147

8

4

 

1000

Sensitivity

–

–

–

–

–

–

–

0.900

0.583

0.753

0.907

0.956

0.993

0.969

1.000

0.925

0.925

PPV

–

–

–

–

–

–

–

0.900

1.000

1.000

0.997

0.876

0.812

0.686

0.616

0.947

0.946

  1. % of cens, percentage of censoring; PPV, positive predictive value
  2. Cells most often selected as the optimal MRCS are shown in italics