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Table 3 Simulation results for cluster model C (two circular clusters, 10% each of total area) with a mean survival time of 7

From: Optimizing the maximum reported cluster size in the spatial scan statistic for survival data

 

% of cens

 

Maximum reported cluster size (MRCS)

Default Setting

3%

4%

5%

6%

8%

10%

12%

15%

20%

25%

30%

35%

40%

45%

50%

Overall

Circular window

10%

Frequency

18

12

11

17

103

48

46

65

19

12

20

39

53

39

26

 

528

Sensitivity

0.005

0.174

0.288

0.284

0.414

0.464

0.478

0.544

0.513

0.597

0.771

0.857

0.943

0.953

0.971

0.588

0.313

PPV

0.982

0.875

0.947

0.931

0.971

0.819

0.724

0.711

0.547

0.484

0.495

0.468

0.451

0.393

0.361

0.694

0.690

30%

Frequency

30

7

15

15

114

46

55

82

28

34

17

26

18

23

17

 

527

Sensitivity

0.007

0.167

0.244

0.256

0.382

0.409

0.444

0.498

0.506

0.674

0.750

0.840

0.917

0.971

0.980

0.500

0.267

PPV

0.967

1.000

0.778

0.967

0.986

0.799

0.736

0.724

0.525

0.525

0.485

0.455

0.439

0.393

0.360

0.734

0.734

50%

Frequency

47

4

17

8

82

24

44

58

26

49

11

23

27

28

17

 

465

Sensitivity

0.011

0.167

0.245

0.250

0.383

0.438

0.451

0.471

0.458

0.692

0.735

0.844

0.874

0.911

0.927

0.505

0.242

PPV

1.000

1.000

0.878

0.833

0.937

0.824

0.733

0.687

0.487

0.535

0.485

0.453

0.431

0.381

0.343

0.697

0.692

70%

Frequency

77

2

15

3

281

46

5

14

7

10

23

27

3

53

25

 

591

Sensitivity

0.016

0.167

0.250

0.250

0.356

0.379

0.383

0.399

0.500

0.658

0.757

0.904

0.778

0.849

0.827

0.424

0.258

PPV

0.987

1.000

0.750

0.600

0.764

0.697

0.582

0.506

0.482

0.492

0.486

0.477

0.378

0.357

0.321

0.691

0.691

Elliptical window

10%

Frequency

4

14

14

17

73

43

54

39

48

55

55

39

39

24

33

 

551

Sensitivity

0.001

0.196

0.268

0.304

0.389

0.446

0.435

0.532

0.547

0.811

0.861

0.949

0.949

0.951

0.975

0.636

0.350

PPV

1.000

0.905

0.869

0.985

0.908

0.826

0.709

0.692

0.574

0.623

0.573

0.530

0.460

0.388

0.354

0.664

0.662

30%

Frequency

14

23

6

22

84

86

52

64

43

50

34

20

22

25

15

 

560

Sensitivity

0.004

0.217

0.236

0.299

0.367

0.420

0.431

0.475

0.574

0.777

0.851

0.900

0.905

0.960

0.983

0.539

0.304

PPV

1.000

1.000

0.944

0.967

0.936

0.871

0.751

0.666

0.581

0.609

0.548

0.491

0.439

0.400

0.359

0.729

0.729

50%

Frequency

27

26

9

20

54

59

39

78

46

50

23

22

20

25

33

 

531

Sensitivity

0.007

0.244

0.222

0.300

0.360

0.412

0.436

0.473

0.533

0.717

0.710

0.845

0.900

0.937

0.927

0.526

0.285

PPV

1.000

1.000

0.861

0.905

0.887

0.802

0.740

0.647

0.542

0.570

0.440

0.465

0.437

0.389

0.339

0.673

0.670

70%

Frequency

34

23

2

54

154

122

17

15

35

14

32

37

40

20

49

 

648

Sensitivity

0.010

0.221

0.208

0.323

0.329

0.336

0.343

0.383

0.521

0.637

0.779

0.887

0.892

0.883

0.959

0.481

0.316

PPV

1.000

1.000

0.708

0.973

0.762

0.594

0.529

0.498

0.536

0.478

0.492

0.484

0.432

0.372

0.357

0.646

0.645

  1. % of cens, percentage of censoring; PPV, positive predictive value
  2. Cells most often selected as the optimal MRCS are shown in italics