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Table 4 Simulation results for cluster model D (one elliptical cluster, 10% of total area) with a mean survival time of 5

From: Optimizing the maximum reported cluster size in the spatial scan statistic for survival data

 

% of cens

 

Maximum reported cluster size (MRCS)

Default Setting

3%

4%

5%

6%

8%

10%

12%

15%

20%

25%

30%

35%

40%

45%

50%

Overall

Circular window

10%

Frequency

14

3

8

196

256

82

20

41

84

57

36

17

20

6

5

 

845

Sensitivity

0.017

0.278

0.500

0.669

0.650

0.689

0.700

0.797

0.863

0.974

0.986

0.971

0.992

1.000

1.000

0.730

0.617

PPV

1.000

0.778

0.800

0.970

0.891

0.697

0.553

0.509

0.461

0.410

0.328

0.270

0.239

0.200

0.172

0.728

0.726

30%

Frequency

6

3

10

240

365

92

7

35

63

44

11

11

4

5

2

 

898

Sensitivity

0.011

0.333

0.617

0.653

0.655

0.714

0.714

0.805

0.833

0.920

0.985

1.000

0.958

0.967

1.000

0.699

0.629

PPV

0.833

1.000

0.860

0.989

0.910

0.678

0.568

0.501

0.453

0.385

0.327

0.270

0.212

0.192

0.182

0.807

0.802

50%

Frequency

3

0

8

87

415

49

7

37

90

84

9

16

16

7

19

 

847

Sensitivity

0.003

–

0.667

0.634

0.659

0.660

0.619

0.766

0.782

0.865

0.926

0.979

0.990

0.929

0.974

0.716

0.612

PPV

0.667

–

0.767

0.966

0.867

0.694

0.531

0.503

0.425

0.353

0.296

0.270

0.227

0.196

0.176

0.698

0.691

70%

Frequency

0

0

2

25

142

9

1

7

25

32

99

32

5

77

40

 

496

Sensitivity

-

–

0.500

0.640

0.612

0.648

0.333

0.762

0.807

0.823

0.978

0.995

0.967

0.903

0.883

0.807

0.426

PPV

-

–

1.000

0.960

0.768

0.707

0.286

0.491

0.444

0.325

0.329

0.265

0.228

0.191

0.171

0.464

0.437

Elliptical window

10%

Frequency

1

5

14

28

67

426

140

101

64

34

15

11

8

4

2

 

920

Sensitivity

0.004

0.300

0.488

0.667

0.704

0.974

0.973

0.965

0.961

0.976

0.978

0.985

0.958

1.000

1.000

0.931

0.857

PPV

1.000

0.800

0.976

0.966

0.945

0.953

0.817

0.657

0.525

0.404

0.327

0.278

0.229

0.205

0.191

0.820

0.820

30%

Frequency

2

2

9

57

68

460

160

96

52

17

8

3

3

2

2

 

941

Sensitivity

0.006

0.333

0.556

0.670

0.696

0.959

0.959

0.953

0.910

0.951

0.958

0.944

0.944

0.917

1.000

0.912

0.858

PPV

0.500

1.000

0.944

0.994

0.973

0.937

0.819

0.663

0.493

0.405

0.305

0.257

0.226

0.174

0.188

0.847

0.848

50%

Frequency

0

3

6

3

54

340

248

134

54

37

11

6

12

4

12

 

924

Sensitivity

–

0.222

0.472

0.722

0.735

0.960

0.962

0.969

0.880

0.896

0.864

0.972

0.958

0.958

0.972

0.934

0.864

PPV

–

0.667

0.944

0.875

0.944

0.939

0.825

0.674

0.473

0.369

0.279

0.265

0.230

0.187

0.182

0.785

0.783

70%

Frequency

0

1

12

13

105

301

18

38

21

41

39

30

60

20

34

 

733

Sensitivity

–

0.333

0.472

0.500

0.730

0.976

0.759

0.886

0.746

0.850

0.897

0.956

0.986

0.942

0.966

0.893

0.657

PPV

–

1.000

0.944

1.000

0.981

0.924

0.667

0.594

0.416

0.349

0.290

0.265

0.241

0.204

0.182

0.692

0.690

  1. % of cens, percentage of censoring; PPV, positive predictive value
  2. Cells most often selected as the optimal MRCS are shown in italics