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Table 5 Simulation results for cluster model E (one elliptical cluster, 30% of total area) with a mean survival time of 5

From: Optimizing the maximum reported cluster size in the spatial scan statistic for survival data

 

% of cens

 

Maximum reported cluster size (MRCS)

Default Setting

3%

4%

5%

6%

8%

10%

12%

15%

20%

25%

30%

35%

40%

45%

50%

Overall

Circular window

10%

Frequency

0

0

0

0

3

24

92

128

62

44

20

334

249

15

29

 

1000

Sensitivity

–

–

–

–

0.500

0.669

0.709

0.790

0.764

0.755

0.830

0.885

0.896

0.890

0.962

0.841

0.810

PPV

–

–

–

–

0.926

0.997

0.994

0.978

0.890

0.849

0.781

0.776

0.757

0.639

0.588

0.826

0.820

30%

Frequency

0

0

0

1

8

18

155

209

83

91

20

257

144

5

9

 

1000

Sensitivity

–

–

–

0.600

0.556

0.536

0.694

0.736

0.692

0.665

0.760

0.882

0.896

0.890

0.933

0.778

0.725

PPV

–

–

–

0.923

0.983

1.000

0.992

0.973

0.918

0.853

0.765

0.775

0.768

0.675

0.577

0.872

0.863

50%

Frequency

0

0

0

0

1

22

69

124

71

94

16

395

193

3

12

 

1000

Sensitivity

–

–

–

–

0.300

0.627

0.612

0.665

0.563

0.632

0.747

0.880

0.900

0.900

0.913

0.785

0.765

PPV

–

–

–

–

1.000

1.000

0.992

0.970

0.960

0.854

0.809

0.778

0.768

0.645

0.557

0.837

0.836

70%

Frequency

3

0

0

0

4

6

8

18

46

45

15

680

32

92

51

 

1000

Sensitivity

0.067

–

–

–

0.200

0.425

0.506

0.697

0.551

0.672

0.770

0.878

0.892

0.872

0.913

0.840

0.836

PPV

1.000

–

–

–

1.000

1.000

0.935

0.941

0.958

0.815

0.758

0.765

0.704

0.624

0.553

0.758

0.758

Elliptical window

10%

Frequency

0

0

0

0

0

2

11

52

42

72

428

273

101

18

1

 

1000

Sensitivity

–

–

–

–

–

0.625

0.696

0.867

0.755

0.765

0.894

0.951

0.959

0.992

1.000

0.899

0.896

PPV

–

–

–

–

–

0.962

0.966

0.930

0.931

0.993

0.980

0.891

0.795

0.709

0.606

0.928

0.933

30%

Frequency

0

0

0

0

1

1

22

49

63

137

543

138

35

9

2

 

1000

Sensitivity

–

–

–

–

0.700

0.550

0.700

0.816

0.652

0.720

0.893

0.936

0.954

0.978

1.000

0.854

0.853

PPV

–

–

–

–

1.000

1.000

0.976

0.927

0.962

0.980

0.983

0.881

0.791

0.680

0.616

0.954

0.956

50%

Frequency

0

0

0

0

0

3

1

41

68

121

512

170

60

21

3

 

1000

Sensitivity

–

–

–

–

–

0.617

0.700

0.762

0.624

0.707

0.894

0.931

0.950

0.983

1.000

0.858

0.858

PPV

–

–

–

–

–

1.000

0.933

0.942

0.981

0.966

0.985

0.856

0.788

0.698

0.619

0.940

0.943

70%

Frequency

0

0

0

0

1

1

3

10

19

49

371

126

260

85

75

 

1000

Sensitivity

–

–

–

–

0.200

0.650

0.633

0.625

0.629

0.722

0.873

0.901

0.952

0.977

0.995

0.899

0.899

PPV

–

–

–

–

1.000

1.000

0.921

0.882

0.996

0.921

0.963

0.801

0.755

0.693

0.617

0.837

0.838

  1. % of cens, percentage of censoring; PPV, positive predictive value
  2. Cells most often selected as the optimal MRCS are shown in italics