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Table 6 Simulation results for cluster model F (one irregular cluster, 20% of total area) with a mean survival time of 7

From: Optimizing the maximum reported cluster size in the spatial scan statistic for survival data

 

% of cens

 

Maximum reported cluster size (MRCS)

Default Setting

3%

4%

5%

6%

8%

10%

12%

15%

20%

25%

30%

35%

40%

45%

50%

Overall

Circular window

10%

Frequency

20

6

13

27

69

37

57

38

33

45

17

20

37

32

45

 

496

Sensitivity

0.005

0.141

0.266

0.279

0.360

0.383

0.418

0.490

0.543

0.656

0.697

0.792

0.963

0.966

0.978

0.563

0.285

PPV

0.950

0.750

0.930

0.951

0.966

0.788

0.719

0.673

0.567

0.568

0.460

0.459

0.481

0.434

0.394

0.674

0.663

30%

Frequency

20

2

15

12

53

21

70

33

49

55

11

17

43

19

40

 

460

Sensitivity

0.004

0.154

0.226

0.282

0.373

0.374

0.409

0.501

0.584

0.641

0.769

0.810

0.964

0.931

0.983

0.575

0.267

PPV

0.950

1.000

0.878

0.979

0.973

0.785

0.775

0.678

0.582

0.557

0.511

0.482

0.484

0.411

0.398

0.670

0.663

50%

Frequency

41

1

36

27

31

11

135

30

50

39

3

15

59

15

26

 

519

Sensitivity

0.008

0.154

0.220

0.271

0.360

0.385

0.404

0.474

0.500

0.602

0.667

0.821

0.979

0.903

0.950

0.498

0.263

PPV

1.000

1.000

0.940

0.938

0.967

0.755

0.754

0.637

0.557

0.534

0.453

0.488

0.491

0.411

0.399

0.700

0.698

70%

Frequency

66

0

16

4

204

30

106

23

24

37

1

1

10

31

109

 

662

Sensitivity

0.015

–

0.226

0.308

0.331

0.382

0.411

0.452

0.583

0.605

0.615

0.769

0.923

0.849

0.924

0.473

0.317

PPV

0.985

–

0.797

0.764

0.787

0.736

0.743

0.607

0.622

0.496

0.421

0.455

0.468

0.394

0.399

0.681

0.681

Elliptical window

10%

Frequency

4

6

14

16

31

49

60

71

104

80

39

49

41

29

26

 

619

Sensitivity

0.001

0.154

0.247

0.313

0.347

0.424

0.512

0.574

0.673

0.779

0.862

0.906

0.934

0.942

0.965

0.668

0.414

PPV

1.000

0.833

0.929

0.972

0.966

0.899

0.879

0.816

0.751

0.659

0.591

0.521

0.477

0.421

0.383

0.716

0.714

30%

Frequency

9

5

5

9

14

34

62

72

79

50

63

60

42

24

33

 

561

Sensitivity

0.002

0.231

0.231

0.325

0.352

0.459

0.529

0.585

0.631

0.800

0.865

0.919

0.951

0.952

0.974

0.704

0.396

PPV

0.944

1.000

0.933

1.000

0.954

0.951

0.932

0.835

0.716

0.666

0.594

0.538

0.498

0.431

0.392

0.705

0.703

50%

Frequency

30

12

10

8

22

26

65

74

93

89

69

50

23

18

24

 

613

Sensitivity

0.009

0.224

0.223

0.317

0.332

0.396

0.501

0.577

0.663

0.792

0.845

0.906

0.953

0.932

0.968

0.650

0.402

PPV

1.000

1.000

0.933

0.888

0.899

0.883

0.904

0.813

0.758

0.667

0.578

0.541

0.490

0.426

0.395

0.726

0.727

70%

Frequency

12

6

5

15

84

210

29

100

247

32

34

17

8

29

18

 

846

Sensitivity

0.007

0.205

0.277

0.303

0.362

0.458

0.480

0.600

0.685

0.762

0.697

0.810

0.817

0.918

0.932

0.578

0.490

PPV

1.000

1.000

1.000

0.911

0.926

0.856

0.846

0.869

0.810

0.654

0.495

0.484

0.434

0.422

0.395

0.797

0.797

  1. % of cens, percentage of censoring; PPV, positive predictive value
  2. Cells most often selected as the optimal MRCS are shown in italics