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Table 1 Baseline and procedure characteristics

From: Characterization of prehospital time delay in primary percutaneous coronary intervention for acute myocardial infarction: analysis of geographical infrastructure-dependent and -independent components

 

All

(n = 603)

Direct admission

(n = 441)

Inter-facility transfer

(n = 162)

P value

Demographic characteristics and history

 Age, years (mean [SD])

67.9 (12.5)

68.0 (12.3)

67.4 (13.1)

0.564

  ≥75 years, n (%)

192 (31.8)

140 (31.8)

52 (32.1)

0.934

 Women, n (%)

138 (22.9)

95 (21.5)

43 (26.5)

0.195

 Previous MI, n (%)

69 (11.4)

55 (12.5)

14 (8.6)

0.329

Presentation at PCI facility

 JCS on arrival

  0/I, n (%)

558 (92.5)

403 (91.4)

155 (95.7)

0.085

  II/III, n (%)

30 (5.0)

27 (6.1)

3 (1.9)

 

  Unknown, n (%)

15 (2.5)

11 (2.5)

4 (2.5)

 

 Killip class on arrival

  1/2, n (%)

418 (69.3)

301 (68.3)

117 (72.2)

0.639

  3/4, n (%)

88(14.6)

67 (15.2)

21 (13.0)

 

  Unknown, n (%)

97 (16.1)

73 (16.6)

24 (14.8)

 

Comparison of situations at symptom onset

 Location at STEMI onset

 

  Urban medical regions, n (%)

311 (51.6)

265 (60.1)

46 (28.4)

<0.001*

  Rural medical regions, n (%)

292 (48.4)

176 (39.9)

116 (71.6)

 

 Witness

  Yes, n (%)

311 (51.6)

237 (53.7)

74 (45.7)

0.079

  No, n (%)

292 (48.4)

204 (46.3)

88 (54.3)

 

 Season

  Summer, n (%)

282 (46.8)

202 (45.8)

80 (49.4)

0.462

  Winter, n (%)

321 (53.2)

239 (54.2)

82 (50.6)

 

 Day of onset

  Weekday, n (%)

416 (69.2)

307 (69.9)

109 (67.3)

0.533

  Weekend or holiday, n (%)

185 (30.8)

132 (30.1)

53 (32.7)

 

 Time of onset

  Daytime, n (%)

365 (60.5)

261 (59.2)

104 (64.2)

0.264

  Nighttime, n (%)

238 (39.5)

180 (40.8)

58 (35.8)

 

Transport path

 EMS call

  Yes, n (%)

405 (67.2)

345 (78.2)

60 (37.0)

<0.001*

  No, n (%)

198 (32.8)

96 (21.8)

102 (63.0)

 

 Use of air transportation, n (%)

7 (1.2)

0

7 (4.2)

–

Mechanical support/interventions additional to primary PCI

 IABP, n (%)

71 (11.8)

53 (12.0)

18 (11.1)

0.887

 CABG,n (%)

10 (1.7)

7 (1.6)

3 (1.9)

0.733

Time course

 TIT, min (median [IQR])

185 (125, 290)

160 (114, 255)

259 (170, 359)

<0.001*

 ODT, min (median [IQR])

104 (56, 204)

80 (50, 153)

197 (120, 305)

<0.001*

 ODT ≤ 120 min achieved, n (%)

339 (56.2)

298 (67.6)

41 (25.3)

<0.001*

 DBT, min (median [IQR])

63 (44, 90)

67 (47, 95)

54 (35, 70)

<0.001*

 DBT ≤ 90 min achieved, n (%)

454 (75.3)

318 (72.1)

136 (84.0)

0.003*

 FMCTB, min (median [IQR])

98 (71, 144)

88 (66, 200)

130 (95, 193)

<0.001*

 FMCTB ≤ 120 min achieved, n (%)

405 (67.2)

332 (75.3)

73 (45.1)

<0.001*

 DIDO, min (median [IQR])

40 (13, 72)

–

40 (13, 72)

 

Outcome

 Death (CPC 5), n (%)

38 (6.3)

26 (5.9)

12 (7.4)

0.498

 Poor (CPC 3-5), n (%)

55 (9.1)

38 (8.6)

17 (10.5)

0.478

 Good (CPC 1-2), n (%)

548 (90.9)

403 (91.4)

145 (89.5)

 
  1. We compared categorical variables using the χ2 test or Fisher's exact test and continuous variables using Student's t-test or the Wilcoxon rank-sum test. Variables are expressed as numbers (%), means (SD: standard deviation), or medians (IQR; interquartile ranges). MI, myocardial infarction; JCS, Japan Coma Scale; urban medical regions, Sapporo, Kamikawa Chubu, and Minami Oshima medical regions; rural medical regions, regions outside the urban medical regions; Daytime, 6:00 a.m–6:00 p.m; Nighttime, 6:00 p.m–6:00 a.m; EMS, emergency medical services; PCI, percutaneous coronary intervention, IABP, intra-aortic balloon pump therapy; CABG, coronary artery bypass grafting; TIT, total ischemic time; ODT, onset-to-door time; DBT, door-to-balloon time; FMCTB, first-medical-contact-to-balloon time; DIDO, door-in-to-door-out time; CPC, cerebral performance category
  2. *P < 0.05